Martin González Andrade

2026 (7)

1. Mimila-Cortes A, Arenas-Alatorre J, Jiménez-Duran K, González-Andrade M, Hoz-Rodríguez L, Santana-Vázquez M, Ramírez-González LF, Castro-López KI, Arzate H, Montoya-Ayala G. Cementum Attachment Protein-Derived Peptides Modulate Brushite and Calcium Oxalate Crystallization In Vitro. Journal of peptide science : an official publication of the European Peptide Society. 2026;32(8):e70112. DOI · PubMed · PMID: 42340069
2. González-Andrade M, Lizárraga-Valadez RA, Sosa-Peinado A, Cortés-Benítez F, Vasquez-Martínez N. Uncompetitive Allosteric Inhibition of PTP1B by BP-1-102 Reveals a Potential Dual-Target Strategy toward the PTP1B-STAT3 Oncogenic Axis: Biochemical and Computational Evidence. ACS medicinal chemistry letters. 2026;17(7):1440-1447. DOI · PubMed · PMID: 42445032
3. González-Andrade M, Gijsbers A, Sosa-Peinado A, Vasquez-Martínez N. Rational design framework for fluorescent biosensors from periplasmic binding proteins. Bioscience reports. 2026;46(5). DOI · PubMed · PMID: 41983621
4. Zúñiga-Domínguez JA, Jain R, González-Andrade M, Farquhar ER, Chance MR, Gijsbers A, Sánchez-Puig N. Hydroxyl radical footprinting modification reveals an intradomain communication pathway in EFL1 disrupted by a Shwachman-Diamond syndrome-associated mutation. Protein science : a publication of the Protein Society. 2026;35(4):e70504. DOI · PubMed · PMID: 41848393
5. De-la-Cruz-Martínez L, Equihua-González D, Torres-Chacón DL, Ortiz-Barragán E, Torres-Valencia JM, Martínez-Casares RM, Pérez-Villanueva J, González-Andrade M, Almanza-Pérez JC, Cortés-Benítez F. Targeting Protein Tyrosine Phosphatase 1B (PTP1B) to Improve Insulin Sensitivity Using Indole-Fused Glycyrrhetinic Acid Conjugates with Amino Acids. ACS medicinal chemistry letters. 2026;17(3):679-687. DOI · PubMed · PMID: 41847642
6. Vasquez-Martínez N, Trapala J, Álvarez-Añorve LI, Lizárraga-Valadez RA, González-Andrade M, Sosa-Peinado A. GPU-Accelerated Virtual Screening and Molecular Dynamics Simulations for Identification of Novel DPP‑4 Inhibitors. ACS omega. 2026;11(4):5323-5338. DOI · PubMed · PMID: 41658155
7. López-Sánchez M, Mendoza-Mota H, De-la-Cruz-Martínez L, Matadamas-Martínez F, Torres-Chacón DL, Martínez-Arellano R, Palacios-Espinosa JF, Pérez-Villanueva J, González-Andrade M, Páez-Franco JC, Almanza-Pérez JC, Cortés-Benítez F. Optimization of Indole- and Pyrazole-fused Glycyrrhetinic Acid Derivatives as Potent PTP1B Inhibitors: In Silico, In Vitro, In Vivo, and Metabolomic Studies. ACS bio & med chem Au. 2026;6(1):15-35. DOI · PubMed · PMID: 41726330

2025 (4)

1. De-la-Cruz-Martínez L, Martínez-Arellano R, López-Sánchez M, Alvarado-Rodríguez JG, Torres-Valencia JM, Equihua-González D, Almanza-Pérez JC, Pérez-Villanueva J, González-Andrade M, Páez-Franco JC, Cortés-Benítez F. Impact of C18 Epimerization of Indole- and Pyrazole-Fused 18β-Glycyrrhetinic Acid Derivatives on PTP1B and TCPTP Inhibitory Activity: Synthesis, In Vitro, and In Silico Studies. ChemMedChem. 2025;20(22):e202500350. DOI · PubMed · PMID: 40946227
2. Guerrero-Rodríguez SL, Córdova-Bahena L, Cortés-Mendoza F, Ruiz-Moreno AJ, Mata-Cruz C, Velázquez-Paniagua M, Salinas-Jazmín N, González-Andrade M, Velasco-Velázquez MA. Identification of New CD36 Antagonists by Structure-Based Virtual Screening. Chemical biology & drug design. 2025;106(5):e70205. DOI · PubMed · PMID: 41271444
3. Ramírez-Silva L, Riveros-Rosas H, Hernández-Alcántara G, García-Trejo JJ, Vega-Segura A, González-Andrade M, Díaz-Salazar AJ, Salcedo-Barrientos G. The Functional State of Thermoplasma acidophilum Pyruvate Kinase Relies on an Extra Carboxyl-Terminal Sequence. International journal of molecular sciences. 2025;26(17). DOI · PubMed · PMID: 40943330
4. Arévalo-Salina EL, Nishigaki T, Olvera L, González-Andrade M, Xolalpa-Villanueva W, López-Romero EO, Soberón X, Saab-Rincón G. Change in selectivity of estrogen receptor alpha ligand-binding domain by mutations at residues H524/L525. Biochimica et biophysica acta. General subjects. 2025;1869(4):130775. DOI · PubMed · PMID: 39956471

2024 (5)

1. Del Carmen Navarrete-Mondragón R, Cortés-Benítez F, Elena Mendieta-Wejebe J, González-Andrade M, Pérez-Villanueva J. Virtual and in Vitro Screening Employing a Repurposing Approach Reveal 13-cis-Retinoic Acid is a PTP1B Inhibitor. ChemMedChem. 2024;19(23):e202400452. DOI · PubMed · PMID: 39113101
2. Río IM, González-Andrade M, Portillo FV, Olvera-Carranza C. Exploring the role of the residues into catalytic cavity of inulosucrase from Leuconostoc citreum CW28. International journal of biological macromolecules. 2024;279(Pt 3):135159. DOI · PubMed · PMID: 39214229
3. Coronell-Tovar A, Pardo JP, Rodríguez-Romero A, Sosa-Peinado A, Vásquez-Bochm L, Cano-Sánchez P, Álvarez-Añorve LI, González-Andrade M. Protein tyrosine phosphatase 1B (PTP1B) function, structure, and inhibition strategies to develop antidiabetic drugs. FEBS letters. 2024;598(15):1811-1838. DOI · PubMed · PMID: 38724486
4. Mendoza-Jasso ME, Pérez-Villanueva J, Alvarado-Rodríguez JG, González-Andrade M, Cortés-Benítez F. 3-Benzylaminomethyl Lithocholic Acid Derivatives Exhibited Potent and Selective Uncompetitive Inhibitory Activity Against Protein Tyrosine Phosphatase 1B (PTP1B). ACS omega. 2024;9(30):33224-33238. DOI · PubMed · PMID: 39100322
5. Padilla-Mayne S, Ovalle-Magallanes B, Figueroa M, Linares E, Bye R, Rivero-Cruz I, González-Andrade M, Aguayo-Ortiz R, Mata R. Chemical Analysis and Antidiabetic Potential of a Decoction from Stevia serrata Roots. Journal of natural products. 2024;87(3):501-513. DOI · PubMed · PMID: 37738100

2023 (5)

1. Coronell-Tovar A, Cortés-Benítez F, González-Andrade M. The importance of including the C-terminal domain of PTP1B(1-400) to identify potential antidiabetic inhibitors. Journal of enzyme inhibition and medicinal chemistry. 2023;38(1):2170369. DOI · PubMed · PMID: 36997321
2. Gutiérrez-González JA, Pérez-Vásquez A, González-Andrade M, Galano A, Villaseñor JL, Mata R. Calmodulin-Targeting Molecules from Ageratina grandifolia. Journal of natural products. 2023;86(11):2562-2570. DOI · PubMed · PMID: 37906816
3. Díaz-Rojas M, González-Andrade M, Aguayo-Ortiz R, Rodríguez-Sotres R, Pérez-Vásquez A, Madariaga-Mazón A, Mata R. Discovery of inhibitors of protein tyrosine phosphatase 1B contained in a natural products library from Mexican medicinal plants and fungi using a combination of enzymatic and in silico methods*. Frontiers in pharmacology. 2023;14:1281045. DOI · PubMed · PMID: 38027024
4. Álvarez-Almazán S, Solís-Domínguez LC, Duperou-Luna P, Fuerte-Gómez T, González-Andrade M, Aranda-Barradas ME, Palacios-Espinosa JF, Pérez-Villanueva J, Matadamas-Martínez F, Miranda-Castro SP, Mercado-Márquez C, Cortés-Benítez F. Anti-Diabetic Activity of Glycyrrhetinic Acid Derivatives FC-114 and FC-122: Scale-Up, In Silico, In Vitro, and In Vivo Studies. International journal of molecular sciences. 2023;24(16). DOI · PubMed · PMID: 37628991
5. Trapala J, González-Andrade M, Olvera C, Cayetano-Cruz M, Sanz-Aparicio J, Jimenez-Ortega E, Bustos-Jaimes I, Montiel C. Relevance of aromatic and polar amino acids in the specificity of Inulinase ISO3 from Kluyveromyces marxianus: A molecular dynamics approach with an experimental verification. International journal of biological macromolecules. 2023;242(Pt 1):124734. DOI · PubMed · PMID: 37150366

2022 (5)

1. Pérez-Vásquez A, Díaz-Rojas M, Castillejos-Ramírez EV, Pérez-Esquivel A, Montaño-Cruz Y, Rivero-Cruz I, Torres-Colín R, González-Andrade M, Rodríguez-Sotres R, Gutiérrez-González JA, Madariaga-Mazón A, Mata R. Protein tyrosine phosphatase 1B inhibitory activity of compounds from Justicia spicigera (Acanthaceae). Phytochemistry. 2022;203:113410. DOI · PubMed · PMID: 36030904
2. Sosa-Peinado A, Fructuoso-García K, Vásquez-Bochm LX, González-Andrade M. Bisindolylmaleimides New Ligands of CaM Protein. Molecules (Basel, Switzerland). 2022;27(21). DOI · PubMed · PMID: 36363988
3. Matuz-Mares D, González-Andrade M, Araiza-Villanueva MG, Vilchis-Landeros MM, Vázquez-Meza H. Mitochondrial Calcium: Effects of Its Imbalance in Disease. Antioxidants (Basel, Switzerland). 2022;11(5). DOI · PubMed · PMID: 35624667
4. Sosa-Peinado A, León-Cruz E, Velázquez-López I, Matuz-Mares D, Cano-Sánchez P, González-Andrade M. Theoretical-experimental studies of calmodulin-peptide interactions at different calcium equivalents. Journal of biomolecular structure & dynamics. 2022;40(6):2689-2700. DOI · PubMed · PMID: 33124950
5. Ramírez-Silva L, Hernández-Alcántara G, Guerrero-Mendiola C, González-Andrade M, Rodríguez-Romero A, Rodríguez-Hernández A, Lugo-Munguía A, Gómez-Coronado PA, Rodríguez-Méndez C, Vega-Segura A. The K(+)-Dependent and -Independent Pyruvate Kinases Acquire the Active Conformation by Different Mechanisms. International journal of molecular sciences. 2022;23(3). DOI · PubMed · PMID: 35163274

2021 (3)

1. Rebollar-Ramos D, Ovalle-Magallanes B, Palacios-Espinosa JF, Macías-Rubalcava ML, Raja HA, González-Andrade M, Mata R. α-Glucosidase and PTP-1B Inhibitors from Malbranchea dendritica. ACS omega. 2021;6(35):22969-22981. DOI · PubMed · PMID: 34514267
2. De-la-Cruz-Martínez L, Duran-Becerra C, González-Andrade M, Páez-Franco JC, Germán-Acacio JM, Espinosa-Chávez J, Torres-Valencia JM, Pérez-Villanueva J, Palacios-Espinosa JF, Soria-Arteche O, Cortés-Benítez F. Indole- and Pyrazole-Glycyrrhetinic Acid Derivatives as PTP1B Inhibitors: Synthesis, In Vitro and In Silico Studies. Molecules (Basel, Switzerland). 2021;26(14). DOI · PubMed · PMID: 34299651
3. Díaz-Rojas M, Raja H, González-Andrade M, Rivera-Chávez J, Rangel-Grimaldo M, Rivero-Cruz I, Mata R. Protein tyrosine phosphatase 1B inhibitors from the fungus Malbranchea albolutea. Phytochemistry. 2021;184:112664. DOI · PubMed · PMID: 33524855

2020 (4)

1. Turrubiartes-Martínez E, Bodega-Mayor I, Delgado-Wicke P, Molina-Jiménez F, Casique-Aguirre D, González-Andrade M, Rapado I, Camós M, Díaz-de-Heredia C, Barragán E, Ramírez-Orellana M, Aguado B, et al.. TYK2 Variants in B-Acute Lymphoblastic Leukaemia. Genes. 2020;11(12). DOI · PubMed · PMID: 33260630
2. Salinas-Arellano E, Pérez-Vásquez A, Rivero-Cruz I, Torres-Colin R, González-Andrade M, Rangel-Grimaldo M, Mata R. Flavonoids and Terpenoids with PTP-1B Inhibitory Properties from the Infusion of Salvia amarissima Ortega. Molecules (Basel, Switzerland). 2020;25(15). DOI · PubMed · PMID: 32752292
3. Jiménez-Arreola BS, Aguilar-Ramírez E, Cano-Sánchez P, Morales-Jiménez J, González-Andrade M, Medina-Franco JL, Rivera-Chávez J. Dimeric phenalenones from Talaromyces sp. (IQ-313) inhibit hPTP1B(1-400): Insights into mechanistic kinetics from in vitro and in silico studies. Bioorganic chemistry. 2020;101:103893. DOI · PubMed · PMID: 32492551
4. Meléndez TA, Huanosta-Gutiérrez A, Barriga-Montoya C, González-Andrade M, Gómez-Lagunas F. Dronedarone blockage of the tumor-related Kv10.1 channel: a comparison with amiodarone. Pflugers Archiv : European journal of physiology. 2020;472(1):75-87. DOI · PubMed · PMID: 31897736

2019 (1)

1. Guevara-Flores A, Martínez-González JJ, Herrera-Juárez ÁM, Rendón JL, González-Andrade M, Torres Durán PV, Enríquez-Habib RG, Del Arenal Mena IP. Effect of curcuminoids and curcumin derivate products on thioredoxin-glutathione reductase from Taenia crassiceps cysticerci. Evidence suggesting a curcumin oxidation product as a suitable inhibitor. PloS one. 2019;14(7):e0220098. DOI · PubMed · PMID: 31329647

2018 (3)

1. Rebollar-Ramos D, Macías-Ruvalcaba ML, Figueroa M, Raja HA, González-Andrade M, Mata R. Additional α-glucosidase inhibitors from Malbranchea flavorosea (Leotiomycetes, Ascomycota). The Journal of antibiotics. 2018;71(10):862-871. DOI · PubMed · PMID: 30018423
2. Ochoa-de la Paz LD, González-Andrade M, Pasantes-Morales H, Franco R, Zamora-Alvarado R, Zenteno E, Quiroz-Mercado H, Gonzales-Salinas R, Gulias-Cañizo R. Differential modulation of human GABA(C)-ρ1 receptor by sulfur-containing compounds structurally related to taurine. BMC neuroscience. 2018;19(1):47. DOI · PubMed · PMID: 30075755
3. Rojas-Ortega E, Aguirre-López B, Reyes-Vivas H, González-Andrade M, Campero-Basaldúa JC, Pardo JP, González A. Saccharomyces cerevisiae Differential Functionalization of Presumed ScALT1 and ScALT2 Alanine Transaminases Has Been Driven by Diversification of Pyridoxal Phosphate Interactions. Frontiers in microbiology. 2018;9:944. DOI · PubMed · PMID: 29867852

2017 (4)

1. Peltomaa R, Benito-Peña E, Barderas R, Sauer U, González Andrade M, Moreno-Bondi MC. Microarray-Based Immunoassay with Synthetic Mimotopes for the Detection of Fumonisin B(1). Analytical chemistry. 2017;89(11):6216-6223. DOI · PubMed · PMID: 28475831
2. Flores-Bocanegra L, González-Andrade M, Bye R, Linares E, Mata R. α-Glucosidase Inhibitors from Salvia circinata. Journal of natural products. 2017;80(5):1584-1593. DOI · PubMed · PMID: 28422509
3. Castillo-Hernández JC, Velázquez-Moyado JA, Reyes-Ramírez A, Ramírez-López EG, González-Andrade M, Navarrete A. Effect of N-Benzylpiperazine, Its Metabolite N-Benzylethylenediamine, and Its Disubstituted Analogue N,N'-Dibenzylpiperazine on the Acquisition, Formation, and Consolidation of Memory in Mice. Pharmacology. 2017;99(5-6):268-274. DOI · PubMed · PMID: 28219076
4. Velázquez-López I, León-Cruz E, Pardo JP, Sosa-Peinado A, González-Andrade M. Development of new hCaM-Alexa Fluor(®) biosensors for a wide range of ligands. Analytical biochemistry. 2017;516:13-22. DOI · PubMed · PMID: 27744023

2016 (1)

1. González-Andrade M, Rodríguez-Sotres R, Madariaga-Mazón A, Rivera-Chávez J, Mata R, Sosa-Peinado A, Del Pozo-Yauner L, Arias-Olguín II. Insights into molecular interactions between CaM and its inhibitors from molecular dynamics simulations and experimental data. Journal of biomolecular structure & dynamics. 2016;34(1):78-91. DOI · PubMed · PMID: 25702612

2015 (2)

1. Pardo JP, González-Andrade M, Allen K, Kuroda T, Slayman CL, Rivetta A. A structural model for facultative anion channels in an oligomeric membrane protein: the yeast TRK (K(+)) system. Pflugers Archiv : European journal of physiology. 2015;467(12):2447-60. DOI · PubMed · PMID: 26100673
2. Mata R, Figueroa M, González-Andrade M, Rivera-Chávez JA, Madariaga-Mazón A, Del Valle P. Calmodulin inhibitors from natural sources: an update. Journal of natural products. 2015;78(3):576-86. DOI · PubMed · PMID: 25536331

2014 (2)

1. del Pozo-Yauner L, Wall JS, González Andrade M, Sánchez-López R, Rodríguez-Ambriz SL, Pérez Carreón JI, Ochoa-Leyva A, Fernández-Velasco DA. The N-terminal strand modulates immunoglobulin light chain fibrillogenesis. Biochemical and biophysical research communications. 2014;443(2):495-9. DOI · PubMed · PMID: 24321098
2. Brindis F, González-Andrade M, González-Trujano ME, Estrada-Soto S, Villalobos-Molina R. Postprandial glycaemia and inhibition of α-glucosidase activity by aqueous extract from Coriandrum sativum. Natural product research. 2014;28(22):2021-5. DOI · PubMed · PMID: 24836119

2013 (6)

1. Leyte-Lugo M, Figueroa M, González Mdel C, Glenn AE, González-Andrade M, Mata R. Metabolites from the endophytic [corrected] fungus Sporormiella minimoides isolated from Hintonia latiflora. Phytochemistry. 2013;96:273-8. DOI · PubMed · PMID: 24084473
2. Rodríguez-Ramos F, Navarrete A, González-Andrade M, Alarcón C, Aguilera-Cruz A, Reyes-Ramírez A. Synthesis, docking study and relaxant effect of 2-alkyl and 2-naphthylchromones on rat aorta and guinea-pig trachea through phosphodiesterase inhibition. Bioorganic chemistry. 2013;50:17-25. DOI · PubMed · PMID: 23933402
3. Rivera-Chávez J, González-Andrade M, González Mdel C, Glenn AE, Mata R. Thielavins A, J and K: α-Glucosidase inhibitors from MEXU 27095, an endophytic fungus from Hintonia latiflora. Phytochemistry. 2013;94:198-205. DOI · PubMed · PMID: 23809634
4. Madariaga-Mazón A, González-Andrade M, González Mdel C, Glenn AE, Cerda-García-Rojas CM, Mata R. Absolute configuration of acremoxanthone C, a potent calmodulin inhibitor from Purpureocillium lilacinum. Journal of natural products. 2013;76(8):1454-60. DOI · PubMed · PMID: 23876004
5. González-Andrade M, Del Valle P, Macías-Rubalcava ML, Sosa-Peinado A, Del Carmen González M, Mata R. Calmodulin inhibitors from Aspergillus stromatoides. Chemistry & biodiversity. 2013;10(3):328-37. DOI · PubMed · PMID: 23495150
6. Brindis F, González-Trujano ME, González-Andrade M, Aguirre-Hernández E, Villalobos-Molina R. Aqueous extract of Annona macroprophyllata: a potential α-glucosidase inhibitor. BioMed research international. 2013;2013:591313. DOI · PubMed · PMID: 24298552

2012 (2)

1. Leyte-Lugo M, González-Andrade M, González Mdel C, Glenn AE, Cerda-García-Rojas CM, Mata R. (+)-Ascosalitoxin and vermelhotin, a calmodulin inhibitor, from an endophytic fungus isolated from Hintonia latiflora. Journal of natural products. 2012;75(9):1571-7. DOI · PubMed · PMID: 22924467
2. Escandón-Rivera S, González-Andrade M, Bye R, Linares E, Navarrete A, Mata R. α-glucosidase inhibitors from Brickellia cavanillesii. Journal of natural products. 2012;75(5):968-74. DOI · PubMed · PMID: 22587572

2011 (5)

1. Rodríguez-Ramos F, González-Andrade M, Navarrete A. Gnaphaliin A and B relax smooth muscle of guinea-pig trachea and rat aorta via phosphodiesterase inhibition. The Journal of pharmacy and pharmacology. 2011;63(7):926-35. DOI · PubMed · PMID: 21635258
2. Reyes-Ramírez A, Leyte-Lugo M, Figueroa M, Serrano-Alba T, González-Andrade M, Mata R. Synthesis, biological evaluation, and docking studies of gigantol analogs as calmodulin inhibitors. European journal of medicinal chemistry. 2011;46(7):2699-708. DOI · PubMed · PMID: 21514702
3. Gonzalez-Andrade M, Rivera-Chavez J, Sosa-Peinado A, Figueroa M, Rodriguez-Sotres R, Mata R. Development of the fluorescent biosensor hCalmodulin (hCaM)L39C-monobromobimane(mBBr)/V91C-mBBr, a novel tool for discovering new calmodulin inhibitors and detecting calcium. Journal of medicinal chemistry. 2011;54(11):3875-84. DOI · PubMed · PMID: 21495717
4. Figueroa M, González-Andrade M, Sosa-Peinado A, Madariaga-Mazón A, Del Río-Portilla F, González Mdel C, Mata R. Fluorescence, circular dichroism, NMR, and docking studies of the interaction of the alkaloid malbrancheamide with calmodulin. Journal of enzyme inhibition and medicinal chemistry. 2011;26(3):378-85. DOI · PubMed · PMID: 20939762
5. Brindis F, Rodríguez R, Bye R, González-Andrade M, Mata R. (Z)-3-butylidenephthalide from Ligusticum porteri , an α-glucosidase inhibitor. Journal of natural products. 2011;74(3):314-20. DOI · PubMed · PMID: 20879744

2009 (2)

1. González-Andrade M, Figueroa M, Rodríguez-Sotres R, Mata R, Sosa-Peinado A. An alternative assay to discover potential calmodulin inhibitors using a human fluorophore-labeled CaM protein. Analytical biochemistry. 2009;387(1):64-70. DOI · PubMed · PMID: 19185562
2. Figueroa M, González Mdel C, Rodríguez-Sotres R, Sosa-Peinado A, González-Andrade M, Cerda-García-Rojas CM, Mata R. Calmodulin inhibitors from the fungus Emericella sp. Bioorganic & medicinal chemistry. 2009;17(6):2167-74. DOI · PubMed · PMID: 19013822

2005 (1)

1. Sosa-Peinado A, González-Andrade M. Site-directed fluorescence labeling reveals differences on the R-conformer of glucosamine 6-phosphate deaminase of Escherichia coli induced by active or allosteric site ligands at steady state. Biochemistry. 2005;44(46):15083-92. DOI · PubMed · PMID: 16285712